Creutzfeldtjakob disease essay

Lack of B6 can lead to peripheral neuropathy.

Creutzfeldtjakob disease essay

The survey identified the abnormal protein in a wider age group than before, and in people with all genetic forms of the protein, the researchers wrote today Oct. Although the disease itself is rare, infection with the protein could be quite common, say the authors of an editorial accompanying the study in the journal.

Creutzfeldt - Jakob disease Essays

Variant Creutzfeldt-Jakob disease vCJD is a rare and fatal neurodegenerative disease, known as the human form of bovine spongiform encephalopathy BSEor mad cow disease. The disease is thought to result from an infectious type of protein called a prion, which clump together and cause irreparable brain damage.

The brain of a person infected with vCJD is often riddled with holes, resembling a sponge. Sixteen of these samples tested positive for the abnormal prion protein, which translates to cases per 1 million people, or 1 in 2, people.

A similar number of people born between and tested positive, as with people born between andthe results showed. No differences between men and women, or between geographic living areas, were found. Furthermore, presence of the abnormal protein was not linked to any particular genetic type, or genotype, of the prion gene everyone carries some version of this gene.

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Among the 16 samples that tested positive in the study, there was a higher proportion of a genotype known as "VV" on the prion gene, compared with the general U. But all of the people known to have had the disease had the so-called "MM" genotype, the researchers said.

Creutzfeldtjakob disease essay

People with the "VV" genotype may be more susceptible to developing the disease, or might never show any signs of the disease, the researchers said. Although far fewer people develop Creutzfeldt-Jakob disease than carry the abnormal protein, scientists say additional research is needed to develop blood tests for the protein and to look at tissue from before the disease arises.

Creutzfeldtjakob disease essay

The first cases of Creutzfeldt-Jakob disease arose in the late s and early s, and were linked with exposure to contaminated meat. The United Kingdom has had only clinical cases of vCJD to date, but previous studies have estimated as many as 1 in 4, people may carry the abnormal prions.

Still, it's not clear how many of these carriers will develop the disease, which often has its onset around age Receiving a blood transfusion or undergoing surgery can potentially transmit the disease, so U.Creutzfeldt–Jakob disease (CJD) belongs to the group of human prion diseases – rare neurodegenerative disorders that are caused by transmissible agents known as prions.

In CJD, the levels of prion infectivity are highest in the brain, and there is evidence from experimental models that similar levels of infectivity are likely to be present in the retina and optic nerve. ‍Hans Gerhard Creutzfeldt (June 2, - December 30, ) was a German neuropathologist, who first described the Creutzfeldt-Jakob disease.

He was born in Harburg upon Elbe and died in Munich. He was born in Harburg upon Elbe and died in Munich.

Creutzfeldt-Jakob disease - The Full Wiki

Creutzfeldt-Jakob Disease (CJD) is one prion disease of particular interest and concern to healthcare professionals, including those working in the Central Service/Sterile Processing profession.

CJD is caused by a proteinaceous infectious agent or prion, and is a neurodegenerative disorder with characteristic clinical and diagnostic features. Since Creutzfeldt-Jakob disease is so rare, there are numerous symptoms in which the patient first experiences to be considered for this disease. In the early stages, symptoms will include weakness; changes in sleep patterns; weight loss; and a loss in appetite and/or sex drive (Creutzfeldt-Jakob Disease ).

Abstract. To explore possible risk factors in the past medical history of patients with Creutzfeldt-Jakob disease (CJD), we conducted a case-control study among 26 cases and 40 matched controls.

Sporadic Creutzfeldt-Jakob Disease or CJD: This is the most common category of Creutzfeldt-Jakob disease or CJD. It may affect a person who may have no risk factors associated with Creutzfeldt-Jakob disease or CJD. This type of CJD is present in approximately 80% of the cases.

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